Bio Bench Compact Bioreactor

Bio Bench Compact Bioreactor

Flexible entry-level bioreactor system that is designed for fermentation and cell culture operating modes.

  • Bio Bench Compact Controller offer a wide choice of interchangeable vessels such as stirred tank Re-usable Glass and SUB Single-use disposable from 75mL to 75 Litres working volume and more.
  • Compact footprint to saves valuable space in your laboratory.
  • Bioreactor include the Bioflex TM  supervisory and remote control software suitable for HMI Touch panel interfaces and laptop or desktop PCs and Smart phones.
  • The BIO BENCH COMPACT can be configured for multi purpose applications like bacterial/yeasts fermentation as well as sofisticated cell cultures.

 

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  • Bio Bench Compact Controller offer a wide choice of interchangeable vessels such as stirred tank Re-usable Glass and SUB Single-use disposable from 75mL to 75 Litres working volume and more.
  • The control tower of the Bio Bench Compact is conceived featuring a compact footprint to saves valuable space in your laboratory.
  • The system enable full control of your bioprocess with digital pH and DO probes that help you immediately recognize whether you can use a probe for the next cultivation batch.
  • Moreover, the system has a built-in Gas Mixing system either with rotameters or mass-flow controllers for fermentation and cell culture process as well as a selectable Pumping system for precise liquid addition.
  • The whole Bioreactor system is driven by the BIOFLEX ™ Software that is an intelligent interface easy accessible also for beginners. Thanks to the intuitive user interface, operating the Bio Bench Compact becomes simple, reduces operating errors and speeds up training. The Bioflex Software can be installed on a laptop PC or tablet or smartphone and enables you to monitor and control the Bio Bench Compact at anytime in the laboratory, in the office or even at home.
  • Each of the Bio Bench Compact bioreactors can be equipped with a chiller that effectively removes heat from your culture. This reduces your cooling water usage, and you will not require a water supply line for cooling installed in your lab.
  • The only utility connections you need are electricity and gas supply to operate the Bio Bench Bioreactor.
  • Reliable PLC ‘programmable logic controller’ automation based on industry standard components
  • Fast Load peristaltic pumps for precise liquid addition
  • Accurate Rotameters or automated TMFC mass flow controllers for cell culture process
  • Automated adjustment of PID parameters
  • Higher cell densities with fed-batch processes
  • Convenient data storage and analysis
  • Leading Bioflex software is the ideal tool for experimental design, perform trial runs, as well as analyzing and optimizing media and parameters for cultivation
Specification Bio Bench Compact 
Agitation System Direct drive, mechanical or magnetically coupled drive
Stirrer speed (rpm) Standard range is 1 – 2000 rpm adjustable according to required configuration either bacterial, cell culture or both
Impellers Rushton, marine, pitched Blade, adjustable and removable type impellers. Special impellers are also available
Gas sparger Porous sparger, L-type sparger, Sinterized sparger, fixed or removable type
Gas overlay Available as option
Gas mixing Standard set-up include Air, O2, CO2 and N2 gas mixing station, Rotameters with precision control valve or TMFC mass flow controllers for automatic gas flow control, regulation and data recording
Peristaltic Pumps Standard set-up include 3 Easy-load peristaltic pumps for precise liquid addition. The system is upgradable with 2 additional variable speed.
Exhaust gas Water cooled exhaust gas Condenser
Sampling Sanitary sampling system with Fixed height and Height adjustable sampling pipe including contained sampling bottles
Harvesting Harvest pipe and Dip tube Fixed height or Height adjustable
Liquid additions Triple or single inlet ports for chemicals additions (optional micro liquid injectors).
pH Optical or Digital pH sensors, 12mm, 19mm PG 13.5 Ingold fitting (220mm, 320mm, 420mm length). Intelligent Cascade Control with acid and alkali pumps and/or CO2 gas (Rotameters or TMFC mass flow controllers).
DO2 Optical or Digital DO sensor, 12mm, 19mm PG 13.5 Ingold fitting (220mm, 320mm, 420mm length) Intelligent Cascade Control with Air, O2, N2 (Rotameters or TMFC mass flow controllers), Agitation and Feeding Pumps
Temperature Pt-100 RDT probe. Automated Control of cooling and heating modules. Chiller is also available as optional
Foam Conductivity based foam sensor, high/low foam, height adjustable. Automated Control with anti foam addition pump or other actuators
Level Continuous level monitoring sensor, height adjustable. Automated Control with input and output pumps
Pressure Pressure sensor top plate mounted. PLC and SCADA Software Control: modulated pressure valve, combined with air inlet, Flowmeters / mFC, agitation and other actuators
Weight Load cells and Scales available. Automated Control with input and output pumps
Probes and sensors available Integrated online Biomass sensor, Optical Density probes, Glucose sensor,CO2/O2/NH4/SO2 Gas Analyzer, pCO2 probe

Conductivity, methanol/ethanol analyzers. Automated samplers. Software Control and integration via OPC interface

Photo-Bioreactors Special accessories for photo-synthetic and photo trophic microorganisms, LED light set available in white, blue, red and other colours

Key Competitive Advantages

  • Intuitive Controller and Software interface for entry-level or advanced operating modes
  • Pre-programmed ready to use configurations either for fermentation and cell culture
  • Built-in modules with full range of Sensors , Gas Mixing and Pumping systems for full process control
  • One Controller platform enable to interchange classic stirred tank glass autoclavable and SUB disposable vessels from 75mL to 75L working volume
  • Bio Bench Compact Controller enable Single and Parallel Bioreactors operations
  • Powerful Software Bioflex can supervise and control up to 36 systems working simultaneously and independently.
  • Digital pH and Optical Dissolved Oxygen sensor for improved accuracy and durability.
  • Available integrated online sensors measurement such like Biomass, Optical density, Gas Analyser, Glucose Analyser, Alchool Analyser, pCO2 Analyser and others.
  • Online 24/24h maintenance service and support with remote diagnostics.

 

STR Stirred tank Glass autoclavable Vessels
Total volume Working min. Working vol.
500mL / Single wall / Jacketed 75 mL 400 mL
750mL / Single wall / Jacketed 150 mL 600 mL
1L / Single wall / Jacketed 250 mL 800 mL
2L / Single wall / Jacketed 0,4 L 1,6 L
3L / Single wall / Jacketed 0,6L 2,5L
5L / Single wall / Jacketed 1,0 L 4,0 L
7L / Single wall / Jacketed 1,4 L 5,6 L
10L / Single wall / Jacketed 2,0 L 8,0 L
15L / Single wall / Jacketed 3,0 L 12,0 L
20L / Single wall / Jacketed 4,0 L 16,0 L
SUB Single use Disposable Vessels
Total volume Working min. Working vol.
250mL / Single wall / Jacketed 50 mL 200 mL
500mL / Single wall / Jacketed 75 mL 400 mL
1L / Single wall / Jacketed 250 mL 800 mL
2L / Single wall / Jacketed 0,4 L 1,6 L
3L / Single wall / Jacketed 0,6L 2,5L
6L / Single wall / Jacketed 1,2 L 5,0 L
10L / Single wall / Jacketed 2,0 L 8,0 L
15L / Single wall / Jacketed 3,0 L 12,0 L
20L / Single wall / Jacketed 4,0 L 16,0 L
30L / Single wall / Jacketed 6,0 L 25,0 L
50L / Single wall / Jacketed 10,0 L 40,0 L
75L / Single wall / Jacketed 15,0 L 65,0 L